Classics in Stereoselective Synthesis

Erick M. Carreira

• 17 december 2008
• 9783527299669

Samenvatting:

This book provides a noteworthy compilation of the groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field.

This book provides a noteworthy compilation oft he groundbreaking methods of stereoselective synthesis, belonging to the repertoire of every modern practitioner of synthetic organic chemistry. The general principles underlying these processes are highlighted as they form the basis for the rapid and continuing developments in the field. The work also features illustrative examples of drug and natural product synthesis, resulting in a rich source of stimulating ideas for the efficient use of asymmetric reactions in the construction of sterochemically complex structures.

From the contents:
*Macrocyclic stereocontrol
*Carbonyl addition reactions
*Alpha-Functionalization of enolates
*Aldol and allylation reactions
*Chiral acetals
*Alkene hydroboration, reduction, and oxidation
*Additions to C=N bonds and synthesis of amino acids
*Conjugate additions
*Chiral carbonions
*Metal-catalyzed allylations
*Cyclopropanations and CH-insertion reactions
*Sigmatropic rearrangements
*Diels-Alder and hetero-Diels-Alder reactions
*[3+2]- and [2+2]-cycloaddition reactions