Exosome Communication

Dalapathi Gugulothu

• 15 november 2024
• 9780443290534

Samenvatting:

Exosome Communication: Advances in Research and Therapeutics for Health and Disease serves as a crucial reference for pharmaceutical scientists, focusing on the key qualities of exosomes as drug delivery vehicles. Exosomes are intracellular membrane-based vesicles with diverse compositions, offering significant advantages over traditional drug delivery systems such as liposomes and polymeric nanoparticles, due to their nonimmunogenic nature. This book provides a comprehensive exploration of exosomes, starting with their history and development, understanding extracellular vesicles and biogenesis, and techniques for isolation and characterization. This book also addresses critical considerations like quality control, heterogeneity reduction, regulatory and ethical aspects, clinical trials, and scale-up manufacturing. - Comprehensive Coverage: Detailed exploration of the research history, development, and different isolation techniques of exosomes. - Therapeutic Applications: In-depth discussion of the diverse therapeutic applications of exosomes in health and disease. - Development Challenges: Insightful analysis of the challenges for the development of exosome nanovesicle-based formulations for drug delivery.