Imaging Blood-Brain Barrier Dysfunction in Brain Disorders

Danny J.J. Wang

• 25 november 2025
• 9780443329753

Samenvatting:

Imaging Blood-Brain Barrier Dysfunction in Brain Disorders delves into the intricate structure and function of the blood-brain barrier (BBB), examining its essential role in the pathogenesis of various brain disorders. The book offers a comprehensive overview of cutting-edge medical imaging technologies for visualizing BBB function, both in a healthy state and under diseased conditions. Readers will gain an in-depth understanding of how the BBB influences normal brain function, including aspects such as aging and sleep, and how its dysfunction is linked to serious neurological conditions.Furthermore, the book explores BBB anomalies in brain disorders like stroke, traumatic brain injury, cerebral small vessel disease, Alzheimer's disease, and sleep apnea. It highlights modern medical imaging technologies, such as MRI, for observing BBB function in vivo. It emphasizes the importance of BBB imaging for monitoring and potentially curing brain disorders, and discusses its potential in the early detection of neurological disorders, allowing for timely and effective treatment strategies. - Explains the biology of BBB, its role in maintaining the normal brain function (e.g. aging and sleep), and its aberrations in brain disorders (e.g. stroke, cSVD, AD, TBI, sleep apnea) - Shows how modern medical imaging technologies, in particular MRI, can visualize BBB function in both the healthy and diseased brain - Includes multimedia contents, including videos and graphic illustrations to help readers understand the materials